Beilstein J. Nanotechnol.2015,6, 570–582, doi:10.3762/bjnano.6.59
. The NPs were investigated with regard to their different photocatalytic cytotoxic effects in human malignant melanoma (HT144) and normal (HCEC) cells. The ZnO:Agnanocomposites killed cancer cells more efficiently than normal cells under daylight exposure. Nanocomposites having higher Ag content (10
nanocomposites could provide a new therapeutic option to selectively target cancer cells.
Keywords: cancer therapy; cytotoxicity; photo-oxidation; ZnO:Agnanocomposites; Introduction
Zinc oxide (ZnO) nanoparticles (NPs) exhibit an excellent photo-oxidation activity [1] and are considered as potential
photocatalytic decomposition process is slow and needs to be improved [24]. Therefore, it is interesting to enhance their photocatalytic ability and anticancer activity by forming nanocomposites with other materials, including metal ions such as silver (Ag) or iron (Fe) ions [25]. The ZnO:Agnanocomposites
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Figure 1:
SEM images of the different zinc oxide nanoparticles. (a) ZnO, (b) ZnO:Ag (1%), (c) ZnO:Ag (3%), (d...